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Nausea, vomiting, diarrhea, and constipation affected 60 to 80% of participants at higher doses, though most symptoms were mild to moderate in severity

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At its highest dose, 36 mg, participants in a phase 3 trial lost an average of 12.4 percent of their starting weight over 72 weeks

And it did work

LX1001 is injected into the spinal canal where it diffuses to reach the spinal fluid and brain

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