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The underlying biology doesn't change when you stop: hunger hormones return to pre-treatment levels, energy expenditure decreases, and appetite rebounds

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The timing concern is purely mechanical, related to gastric emptying rate and pH exposure

10.1016/j.semcancer.2022.06.014 142 NaseerF

Making the Right Choice for Your Situation Choosing between Retatrutide vs Tirzepatide depends on several personal factors and your current situation

This is why we recommend starting at a lower dose and increasing slowly- it truly helps let your body adjust to limit side effects