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It was not until a genetically engineered strain of Pseudomonas denitrificans was used, in which eight of the genes involved in the biosynthesis of the vitamin had been overexpressed, that the complete sequence of methylation and other steps could be determined, thus fully establishing all the intermediates in the pathway

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David Field, lead author of the study and associate professor at the University of Readings School of Psychology and Clinical Language Sciences

Rudin et al, 2004)

Sourcing If youre exploring any of these compounds, sourcing matters enormously