The cagrilintide dosing protocols are still being established, but the mechanism of action, targeting amylin receptors for appetite regulation, offers a novel pathway distinct from GLP-1 agonism
doi: 10.1016/j.obpill.2023.100098
We selected SGLT-2 inhibitors and DPP-4 inhibitors as active comparators, because they are used at a similar disease stage as GLP-1 and are not associated with the outcome
Puddu A, Mach F, Nencioni A, Viviani GL, Montecucco F (2013) An emerging role of glucagon-like peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes
doi:10.2147/PRBM.S49114
As well, QCN attenuates vascular dementia-induced neuropsychiatric disorders by improving cerebral blood flow and inhibiting microglia both in vitro and in vivo (Tan et al