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Comprising a short chain of nine amino acids, DSIP is recognized for its role in modulating sleep-wake cycles, neuroendocrine function, and stress responses

Additionally, IGF-1 levels, the primary mediator of many GH effects, show dose-dependent increases in response to combined CJC-1295 and Ipamorelin treatment in rodent models

Kumar M., et al

Multiple Cellular Pathways in Skin Repair Laboratory studies report effects on collagen synthesis, glycosaminoglycan production, MMP-2 expression, TIMP-1 and TIMP-2, and extracellular matrix remodeling in fibroblast or wound-related models [4], [5], [12]

It is best to start treating melasma as soon as you notice it