PMID: 42 HamasakiHMorimitsuS
An injectable form is considered far more effective than topical, as it works systemically and bypasses the top layer of the skin
The studys investigator, Henning Bliddal, MD, is intrigued by whether or not theres a specific action of GLP-1 receptor agonists on the joint, not through weight loss but by itself. In addition to pain and weight reduction, those studied also had improved WOMAC physical function scores from baseline
Semaglutide itself may cause nausea or vomiting, which could add to GI discomfort
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People gain weight after stopping Ozempic because the medications appetite-suppressing effects wear off, causing hunger signals to return