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Kit contents, timing, and use instructions are provided only after approval and should be followed exactly as directed by the clinician

Eli Lilly's orforglipron is an investigational once-daily oral small molecule GLP-1 that does not carry restrictions on food and water intake, while retatrutide is a first-in-class once-weekly triple hormone receptor agonist activating GIP, GLP-1, and glucagon receptors [2]

Schmidt L, Duh FM, Chen F, Kishida T, Glenn G, Choyke P, et al

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Chen TY, Chen J, Tang Y, Zhou J, Guo Y, Chang WC (2020) Angew Chem 132:74377441