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Of note, by the end of an 11-day period, EE in control mice weight-matched to the semaglutide group by food restriction was reduced, whereas EE in the semaglutide-treated group returned to baseline levels

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Off-label use refers to prescribing a drug for a purpose other than that approved by the FDA

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Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening

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