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It's important to remember that while side effects can be uncomfortable, serious side effects are less common, and the benefits of semaglutide often outweigh potential negatives

Think of these hormones as messengers communicating with your brains appetite control centre, helping you feel fuller for longer while lowering the feeling of food noise

[2] This consistent presence means the medication continuously influences how the body responds to carbohydrate intake, regardless of when meals are consumed

Semaglutide 2.4 mg (Wegovy): ~15% body weight loss at 68 weeks in clinical trials Tirzepatide 15 mg (Zepbound): ~21% body weight loss at 72 weeks in clinical trials Real-world data shows lower results: Cleveland Clinic research from 2025 found average weight loss of 7.7% with semaglutide and 12.4% with tirzepatide at one year in routine clinical practice

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doi: 10.1021/acsnano.4c11219 62 ZhangX.LiX.ChenF.CaoX.WangC.JiaoL.et al