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In the phase 2 trial, participants started at 4 mg without escalation experienced significantly more adverse events than those who began at 2 mg

Similarly, other malignant cell lines showed growth inhibition effect with 0.3% (v/v) flaxseed oil including a decrease by 25% for HeLa, 75% for MCF-7, and 50% for both MDA-MB-231 and MDA-MB-468 cells

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Upon swelling boost, IB kinases phosphorylate IB proteins, leading to their breakdown and allowing NF-B to translocate to the nucleus where it starts transcription of pro-swelling genes