Besides antimicrobial peptides, synthetic amphiphilic polymer constituents can also be designed to disrupt bacterial membranes, leading to the efflux of intracellular substances and thus affecting the bacterias ability to survive [79]
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The second mechanism by which glutathione causes lightening of skin is inhibition of transfer of tyrosinase to premelanosomes for melanin synthesis.[] The third mechanism of tyrosinase inhibition is through its antioxidant effect as it scavenges the free radicals generated in the epidermis following UV light irradiation
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