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Oral semaglutide is indicated for use as an add-on combination therapy (with other glucose-lowering agents, including insulin) or as a monotherapy (in patients who are intolerant to metformin) for type 2 diabetes when diet and exercise do not provide adequate glycemic control
Hypoglycemia risk Although the risk of hypoglycemia with these medications is generally low, combining them could potentially increase this risk, especially in patients also taking insulin or sulfonylureas
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Reprod Biol Endocrinol 3 , 28 (2005)
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