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This is an important mechanism for maintaining normal pH, allowing excess proton excretion by providing a proton buffer
And for everyone, the unfavorable shift in body composition (less muscle, proportionally more fat) creates what researchers call sarcopenic obesity, arguably the worst metabolic phenotype
Jun 2016;25(2):151-7
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Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain
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