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doi: 10.1172/JCI112855 25 OrskovCHolstJJPoulsenSSKirkegaardP
Automated CT-based AI tools provide biomarkers of body composition changes in patients treated with semaglutides Ozempic, Wegovy, and Rybelsusbeyond what is evident by standard clinical measures, according to an accepted manuscript published in the American Journal of Roentgenology ( AJR )
Less commonly, Ozempic has been linked to vision changes
[1] [2] This leads to reduced calorie consumption and subsequent weight loss
Its primary role is to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner
Rybelsus may be the better option for patients who: Have BMI greater than 30 and need significant weight loss support Have A1C greater than 9% requiring aggressive glycemic control Are injection-averse but want GLP-1 benefits Are at high risk for heart problems, regardless of existing diagnosis Do not have gastroparesis or history of medullary thyroid cancer Jardiance may be recommended for patients who: Have established cardiovascular disease or heart failure Have chronic kidney disease (eGFR 30-90 mL/min/1.73m) Are cost-sensitive and need a more affordable option Prefer flexible dosing without strict meal timing Do not have recurrent urinary tract infections or hypotension Combination therapy may be appropriate for patients with A1C greater than 10% despite metformin therapy, or those who would benefit from both cardiovascular protection and weight loss
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