K.JugulamM.et al
For mild, asymptomatic increases in heart rate, a period of watchful waiting with regular monitoring may be appropriate
These adverse events primarily included mild to moderate gastrointestinal disorders, with no severe hypoglycemia and a safety profile consistent with the GLP-1 receptor agonist class
While various GLP-1 RAs such as Semaglutide (Wegovy, Ozempic), Dulaglutide (Trulicity), Lixisenatide (Adlyxin), and Tirzepatide (Mounjaro, Zepbound) are commonly prescribed, their specific pharmacokinetics and effects on gastric motility vary, adding complexity to perioperative care (Almandoz et al
B12 is water-soluble, so excess amounts are usually excreted in urine
Critically, the STEP 4 trial showed that patients who discontinued semaglutide regained two-thirds of their lost weight within a year which has major implications for how you think about long-term access and cost sustainability