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In the ischemic environment, microglia tend to polarize toward the M1 phenotype, releasing pro-inflammatory factors such as IL-1 and TNF-, while also activating oxidative stress and matrix metalloproteinases, leading to degradation of tight junction proteins and endothelial dysfunction (138)
BMJ 385 , e078225 (2024)
Erratum in: Nutr Metab Cardiovasc Dis
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