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This is achieved because of the nature of FreSHtracer, which can pass through the cell membrane and react with the thiol of GSH in the cell with high efficiency, unlike other fluorescent dyes that have several shortcomings such as irreversibility, slow kinetics [38], and low fluorescent quantum yields [39]

Potter JD, Robertson SP, Johnson JD

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Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 60 , 3844, doi: 10.1016/j.fct.2013.07.008 (2013)

Furthermore, it has been reported that fatigue induced by progressive disease is often coupled with weight loss and anorexia [24]