PMID 23303275
It also found patients taking the highest dose of the oral GLP-1 agonist, which is currently in development for type 2 diabetes and weight management treatment, lost an average of 7.6% of their body weight
The primary outcome was to evaluate the safety and tolerability of LY3437943 and the secondary outcomes were the pharmacokinetics and pharmacodynamics of the medication
Severe Gastrointestinal Disease: Zepbound is associated with gastrointestinal side effects, such as nausea, diarrhea, vomiting, constipation, and stomach pain, and can sometimes be severe
But recent studies in children and pregnant women have revealed that even mild snoring can negatively affect health, behavior and quality of life
However, these peptide-based biologics are complex and costly to make, requiring specialized facilities and lengthy scale-up timelines