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The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
B6), Riboflavin (Vit.B2), Maltodextrin, Cyanocobalamin (Vit
Jenner P, Dexter DT, Sian J, Schapira AH, Marsden CD
They are well-tolerated for extended periods and are often preferred as first-line treatment for chronic constipation, particularly when bloating or nausea are prominent symptoms
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