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The NHS lists the common symptoms as: Persistent tiredness, breathlessness and a lack of energy Pins and needles, numbness or tingling in the hands and feet A sore, red tongue and mouth ulcers Problems with memory, concentration and mood Pale or slightly yellow-tinged skin If several of these sound familiar and you are on long-term metformin, that is a good reason to ask your GP for a B12 blood test rather than to book an injection straight away
Related: see more drugs in our drug list, plus gastroenterology and nutrition reading
Cyanocobalamin : The most widely available synthetic form
An oral supplement has to travel through your digestive tract, survive stomach acid, bind to a protein called intrinsic factor, and be absorbed in the small intestine
Oral supplementation has shown effectiveness but may not match the efficacy of IM in certain scenarios
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