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Interestingly, ALS and frontotemporal dementia (FTD) are closely related conditions and often share both genetic and disease mechanisms, especially in people with C9ORF72 mutations suggesting they may be part of the same disease spectrum (Parobkova and Matej, 2021)
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
KPV has the strongest preclinical case for gut inflammation
Give your nervous system a break from constant input
Measured Wound Fluid Concentrations: In human wound fluid collected after abdominal surgery, T4 reached concentrations up to 20 mg/L immediately post-surgery, declining to approximately 1 mg/L within 60 hours (PMID 17495244)
Increased energy: Because it can activate NO pathways, BPC-157 may help provide an energy boost
