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Some of the most common reasons include: Cost: GLP-1 drugs can run over $1,300 a month, and theyre not always covered by insurance

Behav Brain Res 205(1):265271 Liu J, Pang ZP (2016) Glucagon-like peptide-1 drives energy metabolism on the synaptic highway

The counter-argument is that a second receptor pathway is a second source of variability in effect, in tolerability, and in long-term safety questions