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Volcano plots ( Figures 3c, d ) were constructed to highlight differentially expressed genes (DEGs) between both comparisons, and genes that overlapped between primary and metastatic tissue were highlighted

Proc Natl Acad Sci USA 104, 1394213947 (2007)

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The most common reason for discontinuation is not lack of efficacy but side effects during titration, cost, or loss of insurance coverage

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