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Limitations of animal studies for predicting toxicity in clinical trials
The interaction between necroptosis and NLRP3 inflammasome plays a crucial role in promoting AILI [264]
The result showed Cyclobutyl tridecyl phthalate had a score of -8.7 followed by Phthalic acid, 4-cyanophenyl nonyl ester -7, then by 1,3-Dioxolane, 4-ethyl-5-octyl-2,2-bis(trifluoromethyl)-, trans- with -6.9 lastly Pentalamide with a score of -6.3, Meta-chlorambucil was used as control which had a score of -5.6
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