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For example, if the desired dose is 250 mcg: Required volume = Desired dose Concentration 250 mcg 500 mcg/mL = 0.5 mL In this example, 0.5 mL of solution contains 250 mcg of peptide
36-38 Adverse reactions and tolerability: The most common adverse reactions associated with SGLT- 2 inhibitor therapy include an increased risk of certain infections and volume status-related events
Reconstitution 3-step visual Reconstitute , add bacteriostatic water down the wall of the vial Measure , use the calculator (section 8) to compute the required volume Store , refrigerator 2 to 8 C, protect from light Detailed protocol What you will need: A vial of AOD-9604 (5 mg lyophilizate) 2 to 2.5 ml of bacteriostatic water (contains 0.9 % benzyl alcohol, a preservative that prevents bacterial growth) Insulin syringe 1 ml / 29G Procedure: Allow the vial of AOD-9604 to reach room temperature (15 to 20 min)
10.1038/304368a0 48
Harrison SA, Ruane PJ, Freilich B
