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The primary endpoint was the percent change in body weight over the 72 weeks, and the key secondary endpoints were a weight reduction of at least 10%, 15%, 20%, and 25% and a change in waist circumference

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In reality, a medical review and specific BMI thresholds usually apply

Semaglutide helps reduce appetite and cravings, supporting steady, medically supervised fat loss

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10.1038/s41598-022-19560-3 49 LiX.YuY.GorshkovB.HaighS.BordanZ.WeintraubD.et al (2018)