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Too little peptide and gene expression changes remain subtle
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[10] 6 injections of 30 nmol/kg over one week , with a one-week follow-up, in 18 chronic psychophysiological insomniacs
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In assays of neurotrophic activity, Dihexa has been found to be seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF), with demonstrated improvements in cognitive function in animal models of Alzheimers disease-like impairment
For context, the toxic dose is estimated at roughly 22,500 mg, compared to a typical weekly dose of about 6 mg
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