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Furthermore, prescription medications in this class carry an FDA warning regarding thyroid tumors based on animal studies
In unimolecular GLP-1R/GCGR dual agonist studies 14,15,16,17 , the ratios of the GLP-1R and GCGR potencies have varied and typically have been significantly greater than 1:1 despite evidence that an evenly balanced, 1:1 ratio results in optimal metabolic effects 18
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However, there is no prioritized recommendation between glucose-lowering agents or weight-loss drugs, apart from avoiding sulfonylureas that can cause weight gain
However, some major insurance companies are known to be more flexible with GLP-1 approvals
