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At the same time, insulin resistance weakens the bone-building signal, creating the diabetic bone paradox, where bones appear dense but fracture more easily.The lecture then explores bone-derived hormones, especially osteocalcin and lipocalin-2
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This potential generic entry date is based on TO REDUCE THE RISK OF SUSTAINED ESTIMATED GLOMERULAR FILTRATION RATE (EGFR) DECLINE, END-STAGE KIDNEY DISEASE, AND CARDIOVASCULAR DEATH IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND CHRONIC KIDNEY DISEASE
It works by increasing insulin release and reducing excess glucose production in the liver
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