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3.4 The regulatory role of autophagy and Nrf2 The main mechanisms that control inflammatory process and prevent self-destruction are autophagy and Nrf2
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These hormones influence multiple metabolic processes, including appetite regulation, energy expenditure, and fat storage [11]
TNF--mediated caspase activation, PI3K/Akt inhibition, TGF-1-driven extracellular matrix remodeling, RhoA/ROCK activation, AGERAGE inflammatory amplification, and sympathetic catecholamine signaling jointly contribute to the deterioration of corpus cavernosum structure and function
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