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Classical pro-inflammatory cytokines (IL1B, IL6, TNF) and pattern recognition receptors (TLR2, TLR4) are markedly increased, along with adhesion molecules (VCAM1, ICAM1) and chemokines (CCL2, CXCL8) that promote leukocyte recruitment and vascular injury (Falco-Holanda et al., 2021
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The software used for data processing was Analyst Software version 1.6.1 (AB Sciex) and MultiQuant Software version 2.0.2 (AB Sciex)
In models of hypertension, BPC-157 showed blood pressure-lowering effects, while in hypotensive states, it supported pressure normalization, suggesting homeostatic regulation rather than unidirectional cardiovascular effects
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