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When this enzyme is overwhelmed, and too much-oxidized GSSG accumulates (compared to the active GSH), your cells become susceptible to damage

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This distinction matters for researchers: while MT-1 benefits from an extensive published clinical pharmacokinetic dataset generated through the EMA-approved Scenesse programme, the evidence base for MT-2 is entirely preclinical and in vitro in nature

Dosing protocols compared The practical aspects of dosing matter enormously for researchers

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