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Structural plasticity among glutathione transferase phi members: natural combination of catalytic residues confers dual biochemical activities

TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice

A 2008 review by Pickart in the Journal of Biomaterials Science summarized GHK-Cu's documented roles in wound healing, dermal remodeling, and skin elasticity, finding that the complex modulates both synthesis and degradation pathways in the extracellular matrix