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Effects of High vs
Constipation: Some users may experience the opposite problem difficulty passing stools or a reduced frequency of bowel movements
The STEP trials showed that symptoms were most pronounced during the 16-week titration period and diminished significantly once participants reached their maintenance dose (Wilding et al., 2021)
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These can include nausea, vomiting, diarrhea, constipation, abdominal discomfort, reduced appetite, and reflux
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