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Bacterial overgrowth
In line with this observation, the pre-administration of DSePA (2 mg/Kg bodyweight) for five consecutive days significantly improved the 30-day survival of mice against the lethal dose (-rays, 10 Gy) of WBI by preventing lipid peroxidation, DNA damage, and apoptosis in the radiosensitive organs like the spleen and small intestine [88, 89]
10.1016/j.cell.2016.01.013 Cell 210 SharmaA.SethiG.TambuwalaM
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The side-chain guanidyl group of Arg454 interacts with the carboxylate moiety of glycine to orient the substrate for attack on the acyl-phosphate intermediate (Herrera et al., Unlike other organisms, some plants synthesize glutathione analogs in which -alanine, serine, or glutamate replaces glycine in the tripeptide (Figure 4A)
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