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If your situation changes (e.g., if you get pregnant or develop a serious side effect), you might be told to discontinue retatrutide

Weight loss comparison at equivalent time points: Real-world data from the SURPASS trials (for diabetes) showed tirzepatide at 15 mg produced 2.4 kg greater weight loss than semaglutide 1 mg at 40 weeks

Pancreatitis (a swollen pancreas) is a rare but possible side effect

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This binding extends the half-life from minutes to approximately seven days