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Topical use presents lower theoretical risk but should still be discussed with a healthcare provider

Tennessee patients have many options for GLP-1 therapy, including online-only providers and big-box wellness chains

Although peripheral effects of the estradiol-GLP-1 conjugates are anticipated, most evidence suggests that the conjugate acts centrally to suppress food-reward (250)

Wroblewska J, et al

In addition, preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal (HPG) axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, concern new aspects in PCOS which are probably not always related to weight loss