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In contrast, GLP-1 receptor agonist trials have reported average weight reductions exceeding 14% over 68 weeks

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In April, the pharmaceutical company Pfizer announced it would stop developing danuglipron, making it the second medication the company has discontinued because of potentially dangerous liver side effects

This case series provides patient-level data that complement the findings of a meta-analysis by He et al of the association of cholecystitis with GLP-1 receptor agonists, the researchers wrote

At Kings College Hospital London in Dubai, we are among the very few hospitals currently offering access to orforglipron, giving patients early access to this new treatment under proper medical supervision

However, these pens are thought to contain other substances