However, over the next year, initiation slowed and even reversed: with first-time prescribing rates declining 31% by June 2025, reflecting an average month-over-month decrease of 0.004 percentage points
Allow patient to choose site for injection
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Some users may try higher dosages, but starting conservative is recommended 1
This typically manifests as increased fine lines, thinning skin, or generally worse appearance despite consistent product use
Not every patient achieves the weight loss targets they are hoping for, and a meaningful proportion of patients even on maximum doses do not reach the 1520% body weight reduction that clinical guidelines increasingly use as a benchmark for meaningful metabolic benefit