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However, certain circumstances may warrant testing including pre-existing liver or kidney conditions where monitoring organ function during therapy provides appropriate oversight, specific health concerns that might benefit from objective biomarker assessment, desire to objectively measure oxidative stress markers or glutathione status before and during therapy, and medical conditions requiring monitoring for safety reasons

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These systems more closely recapitulate the heterogeneity and complexity of human metabolic processes 12,13,14

Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis

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