tirzepatide vs semaglutide for pcos is showing stronger results than women with PCOS. A step forward in treatment options and better outcomes ahead. 💙 Brian Mattsson Mika Wayment Mattsson Kaden Bickmore Hadlee Bickmore Alexa GLP-1 for PCOS - Weight,

And there are some troubling aspects of the Ozempic gold rush that dont get enough attention

Give any plateau at least three to four weeks before concluding it represents genuine stall rather than normal fluctuation

Overgaard RV, Delff PH, Petri KCC, Anderson TW, Flint A, Ingwersen SH

The table below depicts the timing of when many GLP1 receptor agonists became commercially available

I suspect this is from the glucagon agonism of the drug as glucagon stimulates the formation of extra bile acids/bile salts in the liver which can be very irritating to the intestinal lining causing diarrhea

Additionally, PYY influences adipokine secretion