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In the gastrointestinal tract, metformin effects glucose uptake and absorption, increases glucagon-like peptide-1 (GLP-1) secretion, alters the composition and structure of the gut microbiota, and modulates the immune response
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This peptide combination has become an important research tool for studying endocrine communication, hormonal feedback mechanisms, and the coordinated regulation of the growth hormoneIGF-1 axis
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