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The NO produced binds to the iron in numerous enzymes that contain the metal in their active sites
The increased levels of IFN- and TNF- observed within granulomas supernatants along with the decreased burden of BCG could potentially be from the L-GSH supplement that modulated the cytokines for a more effective response against mycobacterial infection in individuals with T2DM
Under high glucose conditions, endothelial cells can acquire the characteristics of fibroblasts, via endothelial-mesenchymal transition (EndMT), which can contribute to neointimal hyperplasia [47]
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