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Yet, controversial outcomes on the efficacy of metformin have also been reported 21,22,23,24 , that might be attributed to heterogeneity of responses in some patient subgroups
In the other study (180) the oral administration of two antidiabetic phytosterols isolated from Aloe vera lophenol (lophenol and cycloartanol) decreased serum and hepatic concentrations of MCP-1 in Zucker diabetic fatty (ZDF) rats
Akalestou E, Miras AD, Rutter GA, le Roux CW
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Some common side effects encompass nausea, vomiting, diarrhea, abdominal pain, and decreased appetite