Dealing with danger in the CNS: the response of the immune system to injury
What is the most powerful antioxidant glutathione
Under normal physiological conditions, microglia and astrocytes protect neurons by eliminating pathogens and cellular debris, as well as releasing neurotrophic factors, thereby maintaining homeostasis
What the animal studies cannot tell us includes optimal human dosing, population-specific responses (elderly, children, pregnancy), long-term safety in humans, rare side effects that require large sample sizes to detect, and interactions with medications or medical conditions
The decision framework proposed here integrates biological plausibility, translational evidence, safety signals, and technological feasibility
Others report receiving expired vials and waiting weeks for customer support to respond