Retinoic acid is found to enhance tight junction protein expression and reduce bacterial translocation in preclinical sepsis models, potentially mitigating multi-organ dysfunction (Martinez Ramos et al., 2025)
In the UK, its only available as a weight loss treatment if you have a BMI over 30, or over 27 with a weight-related health problem, like pre-diabetes
This deep medical expertise allows them to manage complex health conditions alongside your weight loss safely
For a broader overview of serious and non-serious concerns to discuss with a clinician, see Ozempic Safety Concerns
Because GLP-1 agonists can delay gastric emptying, some people need more time between eating before bed to sleep well, and this increased window without food can also help reduce nighttime reflux and heartburn symptoms, which are sometimes increased with GLP-1 use
Additionally, if you are concerned that your Mounjaro may not be working as expected perhaps because you have been injecting into compromised tissue speak to your prescriber before making any changes to your dose or schedule