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Common Side Effects Some individuals may experience mild nausea, vomiting, diarrhea, or constipation , especially during the first few weeks of treatment

Development and cell biology of the blood-brain barrier

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Neurology 81 , 15961603 (2013)

For acute tendon or ligament injuries, typical anecdotal protocols suggest 250mcg to 500mcg twice daily, often administered near the site of injury for localized effect, though systemic routes are also used