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Injectable semaglutide (Wegovy injection) achieved approximately 15% weight loss in Phase 3 studies
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Ultimately, maximizing long-term results requires viewing tirzepatide as one component of comprehensive obesity management, integrated with lifestyle medicine, behavioral support, and ongoing clinical monitoring to achieve sustained metabolic health improvements
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337 Functional inactivation of DNA repair pathways also enhances sensitivity to chemotherapy and radiotherapy, and this effect is further enhanced by inhibitors of the targeting DNA repair pathways that induce synthetic sensitivity or lethality in DNA repair-deficient cancers (Fig
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