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RE-AIM evaluation of the Veterans Health Administration MOVE

Executive Summary Written by Jonathan Wright, British Clinical Pharmacist Last reviewed: February 2026 Glucagon-like peptide-1 (GLP-1) receptor agonists including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) have transformed the treatment of obesity and type 2 diabetes

They both follow a similar process where the orthodontist designs their patients smile on the computer

A clinician reviews every response and may hold or adjust your dose

Meal timing adjustments may also help break through plateaus, as changing when meals are consumed can affect metabolism and appetite regulation

For a detailed look at what retatrutide does and how it compares to existing drugs, see our retatrutide vs tirzepatide comparison