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Effects of oral -lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double-blind, placebo-controlled trial

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A second PEGylated FGF21, BIO89-100, prevents C-terminal degradation by attachment of a PEG moiety to the amino acid residue adjacent to the FAP cleavage site, resulting in a 2.54 day half-life in healthy volunteers

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Observations include mild injection-site reactions in some subjects

Side effects are rare and typically mild, such as slight discomfort at the injection site or temporary bruising